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Our aim was to report on SA in individuals with PWS, describe its unique characteristics, and offer recommendations for its prevention

Both GLP-1 receptor agonists and metformin are known to cause gastrointestinal issues, but their side effect profiles differ

They enhance glucose-induced insulin release, inhibit glucagon secretion, and notably, foster substantial weight loss, potentially reducing insulin resistance

They are successfully used for the treatment of childhood epilepsies, where several controlled clinical trials have now shown efficacy (Martin et al., 2005